Xiangmin Xu, PhD
Chancellor’s Professor, Anatomy and Neurobiology
Director of the Center for Neural Circuit Mapping
Our research program focuses on neural circuit mechanisms that underlie visual perception, learning and memory, and cognition. Our newest direction is to apply our neural circuit findings towards treating Alzheimer’s disease.
Rozanne Sandri-Goldin, PhD
Chancellor’s Professor and Chair, Microbiology and Molecular Genetics
The studies in my lab are focused on a multifunctional regulatory protein of herpes simplex virus (HSV-1) termed ICP27. We are directing our studies toward a structural analysis of ICP27 and the creation of targeted mutations to determine the structure-function of ICP27 interactions.
Todd Holmes, PhD
Professor and Vice Chair, Physiology and Biophysics
My laboratory has developed pioneering approaches for understanding neural circuits and whole animal behavior. We focus on unraveling the functional operations of neurons in vivo with the goal of understanding integrative neural function from molecules to behavior. Recently, we have discovered novel phototransduction mechanisms that occur directly in neurons that rapidly modulate electrical excitability. Other recent projects include modeling human neurodegenerative diseases using Drosophila as a model system.
Zoran Nenadic, DSc
Professor and Chair, BME, School of Engineering
Neuroengineering (brain-computer interfaces, multisensor extracellular recording); Biomedical signal processing and pattern recognition (supervised and unsupervised signal detection and classification); Large-scale in silico biological neural network models; Biomedical devices and sensors.
Alex Nicolau, PhD
Professor and Chair, Computer Science, School of Information and Computer Science
Research interests: Software, Compilers, Supercomputing, EDA, Parallel Processing
Qing Nie, PhD
Chancellor’s Professor, Mathematics and Dev. & Cell Biology. Director, The NSF-Simons Center for Multiscale Cell Fate Research
Computational single-cell genomics, Systems Biology, Machine-learning, Network Inference, Multiscale Modeling
Chuck Ribak, PhD
Professor Emeritus, Anatomy and Neurobiology, UC Irvine
My laboratory used immunocytochemical labeling methods to analyze changes in neural circuitry in several experimental models of epilepsy. We were the first to show a selective loss of inhibitory, GABAergic neurons and synapses at sites of focal epilepsy in primate motor cortex. We also were the first to show that hilar basal dendrites on granule cells in the dentate gyrus after temporal lobe epilepsy in rats. My research interests mainly involve the connections between local circuit neurons and projection neurons in cortical structures.
Bert Semler, PhD
Professor, Microbiology & Molecular Genetics
RNA virus gene expression; RNA-protein and protein-protein interactions; mechanisms of replication of picornavirus genomic RNAs; mechanisms of translation initiation for viral and cellular mRNA